Welcome to Savtchouk lab

Studying the role of astrocytes and GABAergic interneurons in cerebellar processing


at Marquette University since Oct. 2018!

Milwaukee, WI 53233, USA

Approaches

Two-photon microscopy

Infrared laser visualized using IR-sensitive camera/optics. Savtchouk/Volterra 2017

A relatively non-invasive measurement of brain activity in live tissue, on a massive scale!

Electrophysiology

Electrophysiology action potential traces and raster plots

Monitoring a spectrum of fast electrical activity, from a single synapse to the entire cell, with great temporal resolution and target precision.

Behavior and transgenics

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Linking molecular causes to circuit changes, to behavioral outcomes. Discover and validate treatments for cognitive disorders using simpler models of cognition.

About us

Marquette University, Savtchouk Lab, crated laser components.

New lab, open since October 2018

Iaroslav "Alex" Savtchouk is excited to announce the opening of his new lab at Marquette University, Department of Biomedical Sciences.


(On the left here you can see our new femtosecond lasers getting delivered!)

Visit our Google Scholar page
J Neurosci review article cover, and Cell Reports article artistic illustration image

Research topics

Our core competences include two-photon imaging, electrophysiology, and signal processing. We are interested in understanding how astrocytes and GABAergic interneurons contribute to functioning of the cerebellum and of the rest of the brain.

We are likewise interested in developing new technologies allowing ever-faster, higher-fidelity visualization of brain activity in rodents and, eventually, humans!

Our Publications on Pubmed
A large quartz crystal, originally from Switzerland, on display at the Berlin Natural History Museum

We are always looking to hire talented people!

A limited number of funded job openings for postdocs/lab technicians are available (announcement coming in early 2019).


Meanwhile, we  always look to host scientists at all levels willing to apply for independent financial support. Contact us today to discuss how we can support your fellowship application.


We are also accepting motivated graduate and undergraduate Marquette University students to join our amazing team!  


While you are at it, have a look at this large quartz specimen shown to the left. Like calcite, quartz can be birefringent  —  one of several optical anisotropies  that make some crystals very useful for working with laser light! 


Visit the Department's webpage

Open positions

Why you should join our team

Picture of a Danish Lapidarium exhibit. Overlay "Are you the statue, or the sculptor? Get moving..."

Our lab is fully committed to supporting ambitious people with the resources and mentorship they deserve. Your success is our success! 


We  are always willing to host scientists at all levels with a drive to seek independent financial support. Contact us today to discuss how we can support your fellowship application for the external funding sources.


A limited number of funded job openings for postdocs/lab technicians are also available (announcement coming in early 2019).

We are currently accepting motivated graduate and undergraduate Marquette University students to join our amazing team!  


Would you like to learn cool things while working to understand the brain? Do you want to learn and apply advanced biological and programming techniques for your own experiments?  Are you yearning to apply your physics/math education to a real-world biomedical problem? Are you not afraid to make your own road?

If yes, this lab is probably the right place for you.

Publications

Our public tools:

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Coming soon:

Once ready, this page will host the development versions of our public analysis software and plugins

Large-scale calcium signal exploration and analysis in 3D

Please see our Frontiers paper here for a publicly available versions of the analysis plugins (direct link to the zip in Supplementary is here). This page will host the updated versions with bug fixes.

Links to other labs:

Websites of I. Alex Savtchouk's graduate and postdoctoral advisors:

Andrea Volterra's Lab, University of Lausanne, Switzerland: Neuron-astrocyte interactions


SQ. June Liu's lab, LSU Health Sciences Center, New Orleans, USA: Physiology and function of cerebellar stellate cells

Interesting tools for studying neuronal and astrocytic activity:

Frank Kirchhoff's  paradigm-shifting mice (GFAP-CreERT2, many others): Kirchhoff lab


Bal Khakh's astrocyte-specific viral tools: lab page


Loren Looger's incredible viral tools (neurons and astrocytes) Lab page and Looger lab's Addgene page


Ready-to-inject AAV virus aliquotes from Addgene (Penn Vector core has moved there; also, we had some limited but good experience with UNC vector core and Zurich vector core; and there are many others.)

Get in touch

The PI can be reached at Alex (dot) Savtchouk (at) Marquette (dot) edu

Iaroslav 'Alex' Savtchouk lab, Marquette University

560 N 16th St, Schroeder Complex, Milwaukee, WI 53211, USA

+1(414)288-6779